Investigations

Burkholderia gladioli, cocovenenans, food-poisoning, tempeh, bonkrekic, acid, chemical, Natural Products

Natural Products, Structure Elucidation, Burkholderia, gladioli, Lagria, villosa, insect symbiont, protective symbiosis

Pseudomonas tolaasii is the causative effect of bacterial brown blotch disease in the common button mushroom Agaricus bisporus. Some strains of the genus Mycetocola were identified that can suppress the disease symptoms when inoculated to the mushroom cap prior to infection with P. tolaasii. We investigate the molecular basis of the disease suppressive effect of different Mycetocola species.

Natural Products, Endosymbionts, Rhizopus microsporus, Mycetohabitans, Structure Elucidation, Symbiosis

We investigated the role of chemical signaling between two co-occurring bacteria that each make up more than 10% of the community in iron-rich lakes aggregates (iron snow) by comparative metagenomics and propose a model that shows rapid iron snow formation and ultimately energy transfer from the photic zone to deeper water layers are controlled via a chemically mediated interplay.

We study the transcriptional landscape of C. glabrata and identify differentially expressed genes between pH4 and ph8 as well as between nitrosative stress (GSNO) treatment and controll. Candida glabrata was grown in standard nutrient-rich medium, ph4, ph8 and in GSNO conditions. Paired-end and strand-specific RNA-Seq was performed on three biological replicates after PolyA filtering. A fourth replicate without filtering was sequenced single-end and not strand-specific.