Kirstin Scherlach

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About Kirstin Scherlach:

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SEEK ID: https://data.chembiosys.de/people/131

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Joined: 22nd Nov 2021

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Cryptic Mediators at the Bacterial-Fungal Interface: Mushroom Soft Rot Diseases as Infection Model

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Organisms: Streptomyces rapamycinicus, Candida albicans, Aspergillus nidulans, Aspergillus fumigatus, Janthinobacterium agaricidamnosum, Mycetocola lacteus, Mycetocola tolaasinivorans, Pseudomonas tolaasii, Burkholderia sp. strain B4, Burkholderia sp. strain B7, Burkholderia sp. strain B8, Mycetohabitans endofungorum, Mycetohabitans rhizoxinica, Burkholderia gladioli

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Chemical Ecology of Insect Symbionts

B1

Natural Products, Structure Elucidation, Burkholderia, gladioli, Lagria, villosa, insect symbiont, protective symbiosis

Submitter: Kirstin Scherlach

Studies: An antifungal polyketide associated with horizontally acquired genes sup..., Antibiotic-producing symbionts dynamically transition between plant path..., Chemical warfare between leafcutter ant symbionts and a co-evolved pathogen

Assays: Structure elucidation of lagriamide, Structure elucidation of lagriene, Structure elucidation of secondary metabolites from Escovopsis sp., Structure elucidation of sinapigladioside

Snapshots: No snapshots

Created: 30th Nov 2021 at 10:14

Secondary metabolites of mushroom pathogenic bacteria

B1

No description specified

Submitter: Kirstin Scherlach

Studies: Lipopeptides Synergize in Host Colonization by Pathogenic Burkholderia S..., Structure elucidation of lipopeptides

Assays: MS analyses

Snapshots: No snapshots

Created: 24th Nov 2021 at 11:38

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Chemical warfare between leafcutter ant symbionts and a co-evolved pathogen

B1

No description specified

Submitter: Kirstin Scherlach

Investigation: Chemical Ecology of Insect Symbionts

Assays: Structure elucidation of secondary metabolites from Escovopsis sp.

Snapshots: No snapshots

Created: 30th Nov 2021 at 12:16

An antifungal polyketide associated with horizontally acquired genes supports symbiont-mediated defense in Lagria villosa beetles

B1

No description specified

Submitter: Kirstin Scherlach

Investigation: Chemical Ecology of Insect Symbionts

Assays: Structure elucidation of lagriamide

Snapshots: No snapshots

Created: 30th Nov 2021 at 10:53

Antibiotic-producing symbionts dynamically transition between plant pathogenicity and insect-defensive mutualism

B1

No description specified

Submitter: Kirstin Scherlach

Investigation: Chemical Ecology of Insect Symbionts

Assays: Structure elucidation of lagriene, Structure elucidation of sinapigladioside

Snapshots: No snapshots

Created: 30th Nov 2021 at 10:15

Structure elucidation of lipopeptides

B1

No description specified

Submitter: Kirstin Scherlach

Investigation: Secondary metabolites of mushroom pathogenic ba...

Assays: MS analyses

Snapshots: No snapshots

Created: 30th Nov 2021 at 09:10

Lipopeptides Synergize in Host Colonization by Pathogenic Burkholderia Species

B1

No description specified

Submitter: Kirstin Scherlach

Investigation: Secondary metabolites of mushroom pathogenic ba...

Assays: No Assays

Snapshots: No snapshots

Created: 29th Nov 2021 at 11:03

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B1

No description specified

Submitter: Kirstin Scherlach

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Secondary metabolites of mushroom pathogenic ba...

Study: Structure elucidation of lipopeptides

Organisms: No organisms

SOPs: No SOPs

Data files: MS/MS data burriogladin A, MS/MS data burriogladin B, MS/MS data haereogladin A, MS/MS data haereogladin B, MS/MS data haereogladin C, MS/MS data haereogladin D, MS/MS data haereogladin E

Snapshots: No snapshots

Created: 30th Nov 2021 at 09:13, Last updated: 30th Nov 2021 at 09:43

Structure elucidation of lagriene

B1

No description specified

Submitter: Kirstin Scherlach

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Chemical Ecology of Insect Symbionts

Study: Antibiotic-producing symbionts dynamically tran...

Organisms: No organisms

SOPs: No SOPs

Data files: NMR data lagriene

Snapshots: No snapshots

Created: 30th Nov 2021 at 10:18, Last updated: 30th Nov 2021 at 10:20

Structure elucidation of sinapigladioside

B1

No description specified

Submitter: Kirstin Scherlach

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Chemical Ecology of Insect Symbionts

Study: Antibiotic-producing symbionts dynamically tran...

Organisms: No organisms

SOPs: No SOPs

Data files: NMR data sinapigladioside

Snapshots: No snapshots

Created: 30th Nov 2021 at 10:49, Last updated: 30th Nov 2021 at 10:50

Structure elucidation of lagriamide

B1

No description specified

Submitter: Kirstin Scherlach

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Chemical Ecology of Insect Symbionts

Study: An antifungal polyketide associated with horizo...

Organisms: No organisms

SOPs: No SOPs

Data files: NMR data lagriamide

Snapshots: No snapshots

Created: 30th Nov 2021 at 10:54, Last updated: 30th Nov 2021 at 10:55

Structure elucidation of secondary metabolites from Escovopsis sp.

B1

No description specified

Submitter: Kirstin Scherlach

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Chemical Ecology of Insect Symbionts

Study: Chemical warfare between leafcutter ant symbion...

Organisms: No organisms

SOPs: No SOPs

Data files: MS/MS data of shearinine D and 2 hidden items

Snapshots: No snapshots

Created: 30th Nov 2021 at 12:19

Showing 5 out of a possible 21 Data files Advanced Data files list for this Person with search and filtering

NMR data lagriamide

B1

No description specified

Creator: Kirstin Scherlach

Submitter: Kirstin Scherlach

Investigations: Chemical Ecology of Insect Symbionts

Studies: An antifungal polyketide associated with horizo...

Assays: Structure elucidation of lagriamide

Created: 30th Nov 2021 at 10:55

NMR data sinapigladioside

B1

No description specified

Creators: None

Submitter: Kirstin Scherlach

Investigations: Chemical Ecology of Insect Symbionts

Studies: Antibiotic-producing symbionts dynamically tran...

Assays: Structure elucidation of sinapigladioside

Created: 30th Nov 2021 at 10:50

NMR data lagriene

B1

No description specified

Creator: Kirstin Scherlach

Submitter: Kirstin Scherlach

Investigations: Chemical Ecology of Insect Symbionts

Studies: Antibiotic-producing symbionts dynamically tran...

Assays: Structure elucidation of lagriene

Created: 30th Nov 2021 at 10:20

MS/MS data haereogladin E

B1

No description specified

Creators: None

Submitter: Kirstin Scherlach

Investigations: Secondary metabolites of mushroom pathogenic ba...

Studies: Structure elucidation of lipopeptides

Assays: MS analyses

Created: 30th Nov 2021 at 09:43

MS/MS data haereogladin D

B1

No description specified

Creators: None

Submitter: Kirstin Scherlach

Investigations: Secondary metabolites of mushroom pathogenic ba...

Studies: Structure elucidation of lipopeptides

Assays: MS analyses

Created: 30th Nov 2021 at 09:42

3 hidden items

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Showing 5 out of a possible 10 Publications Advanced Publications list for this Person with search and filtering

Mining and unearthing hidden biosynthetic potential.

B1

Abstract (Expand)

Genetically encoded small molecules (secondary metabolites) play eminent roles in ecological interactions, as pathogenicity factors and as drug leads. Yet, these chemical mediators often evade detection, …

Authors: K. Scherlach, C. Hertweck

Date Published: 23rd Jun 2021

Publication Type: Journal

PubMed ID: 34162873

Citation: Nat Commun. 2021 Jun 23;12(1):3864. doi: 10.1038/s41467-021-24133-5.

Created: 24th Nov 2021 at 10:39

Iron Coordination Properties of Gramibactin as Model for the New Class of Diazeniumdiolate Based Siderophores.

B1

(Show All)

Abstract (Expand)

Gramibactin (GBT) is an archetype for the new class of diazeniumdiolate siderophores, produced by Paraburkholderia graminis, a cereal-associated rhizosphere bacterium, for which a detailed solution …

Authors: S. Gama, R. Hermenau, M. Frontauria, D. Milea, S. Sammartano, C. Hertweck, W. Plass

Date Published: 5th Feb 2021

Publication Type: Journal

PubMed ID: 33006390

Citation: Chemistry. 2021 Feb 5;27(8):2724-2733. doi: 10.1002/chem.202003842. Epub 2021 Jan 14.

Created: 26th Nov 2021 at 13:13

N-Heterocyclization in Gliotoxin Biosynthesis is Catalyzed by a Distinct Cytochrome P450 Monooxygenase.

B1, B2

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Abstract (Expand)

Gliotoxin and related epidithiodiketopiperazines (ETP) from diverse fungi feature highly functionalized hydroindole scaffolds with an array of medicinally and ecologically relevant activities. Mutation …

Authors: D. H. Scharf, P. Chankhamjon, K. Scherlach, J. Dworschak, T. Heinekamp, M. Roth, A. A. Brakhage, C. Hertweck

Date Published: 15th Jan 2021

Publication Type: Journal

PubMed ID: 32835438

Citation: Chembiochem. 2021 Jan 15;22(2):336-339. doi: 10.1002/cbic.202000550. Epub 2020 Oct 5.

Created: 26th Nov 2021 at 16:01

Chemical Mediators at the Bacterial-Fungal Interface.

B1

Abstract (Expand)

Interactions among microbes are key drivers of evolutionary progress and constantly shape ecological niches. Microorganisms rely on chemical communication to interact with each other and surrounding …

Authors: K. Scherlach, C. Hertweck

Date Published: 8th Sep 2020

Publication Type: Journal

PubMed ID: 32660387

Citation: Annu Rev Microbiol. 2020 Sep 8;74:267-290. doi: 10.1146/annurev-micro-012420-081224. Epub 2020 Jul 13.

Created: 24th Nov 2021 at 10:38

Antifungal potential of secondary metabolites involved in the interaction between citrus pathogens.

B1

Abstract (Expand)

Numerous postharvest diseases have been reported that cause substantial losses of citrus fruits worldwide. Penicillium digitatum is responsible for up to 90% of production losses, and represent a problem …

Authors: J. H. Costa, C. I. Wassano, C. F. F. Angolini, K. Scherlach, C. Hertweck, T. Pacheco Fill

Date Published: 9th Dec 2019

Publication Type: Journal

PubMed ID: 31819142

Citation: Sci Rep. 2019 Dec 9;9(1):18647. doi: 10.1038/s41598-019-55204-9.

Created: 24th Nov 2021 at 10:24

View all 10 Publications

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