Cryptic Mediators at the Bacterial-Fungal Interface: Mushroom Soft Rot Diseases as Infection Model
SEEK ID: https://data.chembiosys.de/projects/8
Public web page: Not specified
Organisms: Streptomyces rapamycinicus, Candida albicans, Aspergillus nidulans, Aspergillus fumigatus, Janthinobacterium agaricidamnosum, Mycetocola lacteus, Mycetocola tolaasinivorans, Pseudomonas tolaasii, Burkholderia sp. strain b4, Burkholderia sp. strain b7, Burkholderia sp. strain b8, Mycetohabitans endofungorum, Mycetohabitans rhizoxinica, Burkholderia gladioli
PALs: No PALs for this Project
Project created: 29th Sep 2014
Related items
- People (13)
- Institutions (13)
- Investigations (6+2)
- Studies (5+4)
- Assays (5+8)
- Strains (1+22)
- Data files (29+17)
- Publications (30)
- Presentations (0+13)
- Events (0+1)
- Documents (0+17)
Projects: B1, Total ChemBioSys, RDM training
Institutions: Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, RDM workshop December 2018
https://orcid.org/0000-0002-6954-7376Expertise: Molecular Biology, Microbiology, Microscopy, Biotechnology, molecular cloning
Projects: B1
Institutions: Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute
https://orcid.org/0000-0002-0510-9086Expertise: LC/MS, Microscopy, Analytical Chemistry, Microbiology (basic), Nematodes
Tools: Bioassays guided purification, Chromatography, Genetic modification, Isolation purification and separation, LC/MS, Mass spectrometry, Microbiology, Molecular Biology, MS/MS, NMR, PCR, Spectroscopy and structural analysis
Projects: B1
Institutions: Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute
Projects: B1, Total ChemBioSys
Institutions: Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute
https://orcid.org/0000-0001-7826-3749Expertise: Fermentation, Analytical Chemistry, NMR, HRMS, Structure Elucidation, Spectroscopy, LC/MS, Chemistry
Tools: Chromatography, NMR, PCR, Synthetic chemistry, UV-Vis Spectroscopy, Mass spectrometry, LC/MS, Bioassays guided purification, heterologous expression, Isolation purification and separation
Natural Products, Structure Elucidation, Burkholderia, gladioli, Lagria, villosa, insect symbiont, protective symbiosis
Submitter: Kirstin Scherlach
Studies: An antifungal polyketide associated with horizontally acquired genes sup..., Antibiotic-producing symbionts dynamically transition between plant path..., Chemical warfare between leafcutter ant symbionts and a co-evolved pathogen
Assays: Structure elucidation of lagriamide, Structure elucidation of lagriene, Structure elucidation of secondary metabolites from Escovopsis sp., Structure elucidation of sinapigladioside
Snapshots: No snapshots
Submitter: Kirstin Scherlach
Studies: Lipopeptides Synergize in Host Colonization by Pathogenic Burkholderia S..., Structure elucidation of lipopeptides
Assays: MS analyses
Snapshots: No snapshots
Burkholderia gladioli, cocovenenans, food-poisoning, tempeh, bonkrekic, acid, chemical, Natural Products
Snapshots: No snapshots
Natural Products, Structure Elucidation, Burkholderia, gladioli, Lagria, villosa, insect symbiont, protective symbiosis
Snapshots: No snapshots
Pseudomonas tolaasii is the causative effect of bacterial brown blotch disease in the common button mushroom Agaricus bisporus. Some strains of the genus Mycetocola were identified that can suppress the disease symptoms when inoculated to the mushroom cap prior to infection with P. tolaasii. We investigate the molecular basis of the disease suppressive effect of different Mycetocola species.
Snapshots: No snapshots
Submitter: Kirstin Scherlach
Investigation: Chemical Ecology of Insect Symbionts
Assays: Structure elucidation of secondary metabolites from Escovopsis sp.
Snapshots: No snapshots
Submitter: Kirstin Scherlach
Investigation: Chemical Ecology of Insect Symbionts
Snapshots: No snapshots
Submitter: Kirstin Scherlach
Investigation: Chemical Ecology of Insect Symbionts
Assays: Structure elucidation of lagriene, Structure elucidation of sinapigladioside
Snapshots: No snapshots
Submitter: Kirstin Scherlach
Investigation: Secondary metabolites of mushroom pathogenic ba...
Assays: MS analyses
Snapshots: No snapshots
Submitter: Kirstin Scherlach
Investigation: Secondary metabolites of mushroom pathogenic ba...
Assays: No Assays
Snapshots: No snapshots
Submitter: Kirstin Scherlach
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: Secondary metabolites of mushroom pathogenic ba...
Organisms: No organisms
SOPs: No SOPs
Data files: MS/MS data burriogladin A, MS/MS data burriogladin B, MS/MS data haereogladin A, MS/MS data haereogladin B, MS/MS data haereogladin C, MS/MS data haereogladin D, MS/MS data haereogladin E
Snapshots: No snapshots
Submitter: Kirstin Scherlach
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: Chemical Ecology of Insect Symbionts
Submitter: Kirstin Scherlach
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: Chemical Ecology of Insect Symbionts
Submitter: Kirstin Scherlach
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: Chemical Ecology of Insect Symbionts
Submitter: Kirstin Scherlach
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: Chemical Ecology of Insect Symbionts
Organisms: No organisms
SOPs: No SOPs
Data files: MS/MS data of shearinine D and 2 hidden items
Snapshots: No snapshots
Submitter: Ron Hermenau
Provider Name: Not specified
Provider's strain ID: Not specified
Organism: Pseudomonas tolaasii
Genotypes: deleted 1.7 kb tolA
Phenotypes: -tolaasin
Comment: Pseudomonas tolaasii deficient in tolaasin production due to deletion of a 1.7 kb fragment in NRPS encoding gene tolA
Creator: Kirstin Scherlach
Submitter: Kirstin Scherlach
Investigations: Chemical Ecology of Insect Symbionts
Creators: None
Submitter: Kirstin Scherlach
Investigations: Chemical Ecology of Insect Symbionts
Creator: Kirstin Scherlach
Submitter: Kirstin Scherlach
Investigations: Chemical Ecology of Insect Symbionts
Creators: None
Submitter: Kirstin Scherlach
Investigations: Secondary metabolites of mushroom pathogenic ba...
Studies: Structure elucidation of lipopeptides
Assays: MS analyses
Creators: None
Submitter: Kirstin Scherlach
Investigations: Secondary metabolites of mushroom pathogenic ba...
Studies: Structure elucidation of lipopeptides
Assays: MS analyses
Abstract (Expand)
Authors: H. Buttner, S. P. Niehs, K. Vandelannoote, Z. Cseresnyes, B. Dose, I. Richter, R. Gerst, M. T. Figge, T. P. Stinear, S. J. Pidot, C. Hertweck
Date Published: 14th Sep 2021
Publication Type: Journal
PubMed ID: 34504005
Citation: Proc Natl Acad Sci U S A. 2021 Sep 14;118(37). pii: 2110669118. doi: 10.1073/pnas.2110669118.
Abstract (Expand)
Authors: K. Scherlach, C. Hertweck
Date Published: 23rd Jun 2021
Publication Type: Journal
PubMed ID: 34162873
Citation: Nat Commun. 2021 Jun 23;12(1):3864. doi: 10.1038/s41467-021-24133-5.
Abstract (Expand)
Authors: B. Dose, S. P. Niehs, K. Scherlach, S. Shahda, L. V. Florez, M. Kaltenpoth, C. Hertweck
Date Published: 19th Mar 2021
Publication Type: Journal
PubMed ID: 33739557
Citation: Chembiochem. 2021 Mar 19. doi: 10.1002/cbic.202100089.
Abstract (Expand)
Authors: S. Gama, R. Hermenau, M. Frontauria, D. Milea, S. Sammartano, C. Hertweck, W. Plass
Date Published: 5th Feb 2021
Publication Type: Journal
PubMed ID: 33006390
Citation: Chemistry. 2021 Feb 5;27(8):2724-2733. doi: 10.1002/chem.202003842. Epub 2021 Jan 14.
Abstract (Expand)
Authors: D. H. Scharf, P. Chankhamjon, K. Scherlach, J. Dworschak, T. Heinekamp, M. Roth, A. A. Brakhage, C. Hertweck
Date Published: 15th Jan 2021
Publication Type: Journal
PubMed ID: 32835438
Citation: Chembiochem. 2021 Jan 15;22(2):336-339. doi: 10.1002/cbic.202000550. Epub 2020 Oct 5.